Welcome to the website! My name is Corree (Cornelia) Laule and I’m an MR physicist in the Departments of Radiology and Pathology & Laboratory Medicine at the University of British Columbia in Vancouver, Canada. I am also an associate member of the Department of Physics & Astronomy, a principal investigator at ICORD and a member of the Djavad Mowafaghian Centre for Brain Health. I conduct my research at the UBC MRI Research Centre and in the ICORD building.
I am interested in understanding the microstructural and pathological determinants which govern MR signal measures in central nervous system (CNS) tissue. MR methods I use include myelin water imaging, diffusion (various models), magnetic resonance spectroscopy (MRS), standard magnetization transfer, inhomogeneous magnetization transfer, quantitative T1 and T2, and volumetrics. My key research areas include:
• quantitative MR • T1 and T2 relaxation • MRS • diffusion • brain • spinal cord • multiple sclerosis • CNS diseases • development • aging
• white matter • myelin water imaging • myelin • neurodegeneration • spinal cord injury • histology-MRI correlation •
• in vivo • post mortem • formalin-fixed tissue • lipids •